For clients with insulin-dependent diabetes who undergo a hypophysectomy, what medication adjustment may be necessary?

In clients with insulin-dependent diabetes who undergo a hypophysectomy, an increase in insulin dosage may be necessary due to the surgical removal of the pituitary gland and its role in hormonal regulation. The pituitary gland is responsible for secreting several hormones, including those that influence glucose metabolism and insulin sensitivity.

After the hypophysectomy, the loss of these regulatory hormones can lead to changes in the body's metabolic state, often resulting in reduced insulin sensitivity and increased blood glucose levels. As a compensatory mechanism, the insulin production may need to be adjusted—most frequently upward—to maintain glycemic control. It's also crucial to closely monitor blood glucose levels during this period to ensure adjustments in insulin therapy are appropriate.

The other choices do not address the immediate concerns related to the removal of the pituitary gland and its effect on the insulin-regulating hormones, therefore they would not be relevant adjustments in this clinical scenario.