What is a primary symptom of Addison's disease?

A primary symptom of Addison's disease is adrenal crisis. Addison's disease arises from insufficient production of glucocorticoids and mineralocorticoids due to adrenal gland dysfunction, which can lead to a life-threatening condition known as an adrenal crisis. This occurs when the body experiences significant stress, such as illness or injury, and cannot produce adequate cortisol to manage the stress response. Symptoms of an adrenal crisis include severe fatigue, low blood pressure, confusion, and nausea, and it requires immediate medical intervention to restore normal hormone levels.

While excessive thirst and elevated heart rate can be incidental findings in those with Addison's disease, they are not hallmark symptoms of the condition. Low blood sugar may occur in some cases but is not a primary feature of Addison's disease as it focuses more on adrenal hormone deficiency and its physiological effects on the body. The adrenal crisis is critical to recognize and treat rapidly to prevent severe complications, making it a key symptom of Addison's disease.